SNRI's Serotonin Norepinephrine Re-uptake Inhibitors

SNRI's work by increasing the levels of two of the three neurotransmitters in the brain - serotonin and norepinephrine. SNRI's have reportedly increased efficacy over SSRI's - which only work on serotonin - with comparable side effects. However, there is an additional risk of withdrawal symptoms associated with the use of SNRI's

Commonly prescribed SNRI's include Effexor and Cymbalta.